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The Space Shuttle Columbia lifts off from Launch Pad 39B at 2:19 p.m. EDT Apr. 17 to begin the nearly 17-day STS-90 Neurolab mission. The launch was delayed 24 hours due to difficulty with a network signal processor, which was replaced Apr. 16, on the orbiter. The crew members are Commander Richard Searfoss, Pilot Scott Altman, Mission Specialists Richard Linnehan, D.V.M., Dafydd (Dave) Williams, M.D., with the Canadian Space Agency, and Kathryn (Kay) Hire; and Payload Specialists Jay Buckey, M.D., and James Pawelczyk, Ph.D. Investigations during the Neurolab mission will focus on the effects of microgravity on the nervous system.